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AIRE Polyclonal Antibody

This is a AIRE Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED) .

Synonyms

AIRE, AIRE1, APECED, APS1, APSI, PGA1

Gene ID

326

Swiss Prot

O43918

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human AIRE (NP_000374.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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