ERCC2 Polyclonal Antibody
This is a ERCC2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
ERCC2, COFS2, EM9, TFIIH, TTD, TTD1, XPD
Gene ID
2068
Swiss Prot
P18074
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human ERCC2 (NP_001124339.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa/86 kDa
Observed Molecular Weight
80 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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