AVEN Polyclonal Antibody
This is a AVEN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1’s ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.
Synonyms
AVEN, PDCD12
Gene ID
57099
Swiss Prot
Q9NQS1
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human AVEN (NP_065104.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:1000-1:3000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38 kDa
Observed Molecular Weight
55 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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