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IFT74 Polyclonal Antibody

This is a IFT74 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.

Synonyms

IFT74, BBS20, CCDC2, CMG-1, CMG1

Gene ID

80173

Swiss Prot

Q96LB3

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human IFT74 (NP_001092694.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:1000-1:3000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

42 kDa/69 kDa

Observed Molecular Weight

80 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

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