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TYR Polyclonal Antibody

This is a TYR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

Synonyms

TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3

Gene ID

7299

Swiss Prot

P14679

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human TYR (NP_000363.1) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

42 kDa/60 kDa

Observed Molecular Weight

80 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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