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ALAD Polyclonal Antibody

This is a ALAD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins) . ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Synonyms

ALAD, ALADH, PBGS

Gene ID

210

Swiss Prot

P13716

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human ALAD (NP_000022.3) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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