HLA-DRA Polyclonal Antibody
This is a HLA-DRA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages) . The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Synonyms
HLA-DRA, HLA-DRA1, major histocompatibility complex, class II, DR alpha
Gene ID
3122
Swiss Prot
P01903
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human HLA-DRA (NP_061984.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
28 kDa
Observed Molecular Weight
37 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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