TCF4 Polyclonal Antibody
This is a TCF4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.
Synonyms
TCF4, E2-2, FECD3, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, SEF2-1D, TCF-4, bHLHb19, TCF4
Gene ID
6925
Swiss Prot
P15884
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human TCF4 (NP_001077431.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48-71 kDa
Observed Molecular Weight
60 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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