SIGLEC8 Polyclonal Antibody
This is a SIGLEC8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Sialic acid-binding immunoglobulin (Ig) -like lectins, or SIGLECs, are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule that mediates an association with SLAM-associated protein .
Synonyms
SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L
Gene ID
27181
Swiss Prot
Q9NYZ4
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SIGLEC8 (NP_055257.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44 kDa/46 kDa/54 kDa
Observed Molecular Weight
60 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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