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SOCS3 Polyclonal Antibody

This is a SOCS3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN) -gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Synonyms

SOCS3, ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3

Gene ID

9021

Swiss Prot

O14543

Reactivity

Mouse, Rat

Immunogen

A synthetic peptide of human SOCS3 (NP_003946.3) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

24 kDa

Observed Molecular Weight

33 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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