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HDAC5 Polyclonal Antibody

This is a HDAC5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

HDAC5, HD5, NY-CO-9

Gene ID

10014

Swiss Prot

Q9UQL6

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human HDAC5 (NP_005465.2) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IHC 1:50-1:200 IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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