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NEFL Polyclonal Antibody

This is a NEFL Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Synonyms

NEFL, CMT1F, CMT2E, NF-L, NF68, NFL, PPP1R110

Gene ID

4747

Swiss Prot

P07196

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human NEFL (NP_006149.2) .

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, IF

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IHC 1:50-1:200 IF 1:50-1:200

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Frequently Asked Questions

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