BMI1 Polyclonal Antibody
This is a BMI1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1) . This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.
Synonyms
BMI1, FLVI2/BMI1, PCGF4, RNF51, flvi-2/bmi-1, Bmi1
Gene ID
648
Swiss Prot
P35226
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human BMI1 (NP_005171.4) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
36 kDa
Observed Molecular Weight
42 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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