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GRIN2A Polyclonal Antibody

This is a GRIN2A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Synonyms

EPND, FESD, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate receptor, Glutamate receptor ionotropic N methyl D aspartate 2A, GRIN 2A, GRIN2A, hNR2A, LKS, N methyl D aspartate receptor channel, subunit epsilon 1, N Methyl D Aspartate Receptor Subtype 2A

Swiss Prot

Q12879

Accession Number

NP_000824

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide of human GRIN2A

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.5 mg/mL

Dilution

IHC 1:25-100, ELISA 1:2000-5000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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