VPS33B Polyclonal Antibody
This is a VPS33B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants.
Synonyms
FLJ14848, hVPS 33B, hVPS33B, Vacuolar protein sorting 33 homolog B (yeast), Vacuolar protein sorting 33 homolog B, Vacuolar protein sorting 33B (yeast), Vacuolar protein sorting 33B, Vacuolar protein sorting associated protein 33B, VPS 33B
Swiss Prot
Q9H267
Accession Number
BC016445
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human VPS33B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:30-150, ELISA 1:2000-10000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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