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PPOX Polyclonal Antibody

This is a PPOX Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Synonyms

MGC8485, PPO, PPOX, PPOX, Protoporphyrinogen oxidase, V290M, Variegate porphyria, VP

Swiss Prot

P50336

Accession Number

NP_000300

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human PPOX

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.5 mg/mL

Dilution

WB 1:1000-1:5000, IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

51 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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