PNOC Polyclonal Antibody
This is a PNOC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Nociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids) . Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1), a G protein-coupled receptor. Although similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory.
Synonyms
N/OFQ, N23K, N23K/N27K, Nociceptin, included, nocistatin, Npnc1, OFQ, OFQ/N, Orphanin FQ, Orphanin FQ2, Pnoc, PNOC, ppN/OFQ, PPNOC, pre-pro-N/OFQ, prepronociceptin, pronociceptin, Propronociceptin
Swiss Prot
Q13519
Accession Number
NP_006219
Reactivity
Human
Immunogen
Synthetic peptide of human PNOC
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
