MARK1 Polyclonal Antibody
This is a MARK1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The microtubule matrix within a cell plays a central role in intracellular transport, cell shape during differentiation and chromosome partitioning during mitosis. During these processes, microtubules transition rapidly between stable and dynamic states. MAP/microtubule affinity-regulating kinase 1 (MARK1) is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart.
Synonyms
KIAA1477, MAP/microtubule affinity regulating kinase 1, MAP/microtubule affinity-regulating kinase 1, MARK 1, MARK, Mark1, MARK1, MGC126512, MGC126513, Serine/threonine protein kinase MARK1, Serine/threonine-protein kinase MARK1
Swiss Prot
Q9P0L2
Accession Number
NP_061120
Reactivity
Human
Immunogen
Synthetic peptide of human MARK1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.7 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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