IMPDH1 Polyclonal Antibody

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP) . This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10) . Several transcript variants encoding different isoforms have been found for this gene.

IMDH1, IMP (inosine monophosphate) dehydrogenase 1, IMP dehydrogenase 1, IMPD 1, IMPD, IMPD1, IMPDH 1, IMPDH I, IMPDH-I, Impdh1, Inosine 5' monophosphate dehydrogenase 1, Inosine monophosphate dehydrogenase 1, Inosine-5''-monophosphate dehydrogenase 1, LCA11, RP10, sWSS