ESPL1 Polyclonal Antibody
This is a ESPL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.
Synonyms
Caspase like protein ESPL1, Caspase-like protein ESPL1, ESP 1, ESP1, ESPL 1, Espl1, ESPL1, Extra spindle poles like 1, Extra spindle poles like 1 protein, Extra spindle poles-like 1 protein, FLJ46492, KIAA0165, Separase, Separin, Similar to fission yeast cut1and gene, S
Swiss Prot
Q14674
Accession Number
NP_036423
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human ESPL1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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