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NOD1 Polyclonal Antibody

This is a NOD1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

Synonyms

CARD 4, CARD4, Caspase recruitment domain 4, Caspase recruitment domain containing protein 4, Caspase recruitment domain family member 4, Caspase recruitment domain protein 4, Caspase recruitment domain-containing protein 4, CLR 7.1, CLR7.1, NLR family CARD domain

Swiss Prot

Q9Y239

Accession Number

NP_006083

Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human NOD1

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.8 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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