CAV1 Polyclonal Antibody
This is a CAV1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Synonyms
BSCL3, CAV, CAV1, CAV1, caveolae protein,22 kD, caveolin 1 alpha isoform, caveolin 1 beta isoform, Caveolin 1 caveolae protein 22kDa, Caveolin-1, Caveolin1, cell growth-inhibiting protein 32, CGL3, LCCNS, MSTP085, OTTHUMP00000025031, PPH3, VIP 21, VIP21
Swiss Prot
Q03135
Accession Number
NP_001744
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human CAV1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
20 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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