ALDH5A1 Polyclonal Antibody

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD (+) -dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA) . In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

Aldedehyde dehydrogenase 5 family, Aldehyde dehydrogenase 5 family member A1, Aldehyde dehydrogenase 5A1, Aldehyde dehydrogenase family 5 member A1, ALDH5A 1, Aldh5a1, mitochondrial, Mitochondrial succinate semialdehyde dehydrogenase, NAD (+) dependent succinic se