STX1A Polyclonal Antibody

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

HPC 1, Neuron specific antigen HPC1, Neuron-specific antigen HPC-1, OTTHUMP00000174615, OTTHUMP00000174616, OTTHUMP00000174617, OTTHUMP00000174618, P35-1, STX1, STX1A, STX1A, SYN1A, Syntaxin 1A (brain), Syntaxin 1A brain, Syntaxin-1A