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CHRNA10 Polyclonal Antibody

This is a CHRNA10 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Synonyms

Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit, ACH10, Alpha 10 nAChR, Cholinergic receptor nicotinic alpha 10, Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10, Cholinergic receptor, nicotinic, alpha polypeptide 10, CHRNA 10, CHRNA10, NACHR

Swiss Prot

Q9GZZ6

Accession Number

NP_065135

Reactivity

Human

Immunogen

Synthetic peptide of human CHRNA10

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.5 mg/mL

Dilution

IHC 1:25-1:100

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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