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GFRA3 Polyclonal Antibody

This is a GFRA3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.

Synonyms

GDNF family receptor alpha 3, GDNF family receptor alpha-3, GDNF receptor alpha-3, GDNFR-alpha-3, GDNFR3, GFR-alpha-3, GFRA3, GFRA3, Glial cell line derived neurotrophic factor receptor alpha 3, GPI linked receptor, OTTHUMP00000159486, OTTHUMP00000224020

Swiss Prot

O60609

Accession Number

NP_001487

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide of human GFRA3

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1 mg/mL

Dilution

IHC 1:50-1:150

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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