PTGER4 Polyclonal Antibody

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2) . This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.

EP 4, EP4, EP4R, MGC126583, PE2R4, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostaglandin E receptor 4, Prostaglandin E receptor 4 subtype EP4, Prostaglandin E2 receptor, Prostaglandin E2 receptor EP4 subtype, Prostanoid EP4 receptor, PTGER 2, PTGER 4, PTGE