CD192 Polyclonal Antibody

This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.

C C chemokine receptor type 2, C C CKR 2, C-C chemokine receptor type 2, C-C CKR-2, CC chemokine receptor type 2, CC CKR 2, CC-CKR-2, CCCKR2, CCR 2, CCR-2, CCR1L, CCR2, CCR2, CCR2A, CCR2B, CCR5L, CD192, CD192 antigen, Chemokine C C motif receptor 2, Chemokine CC Motif Recep