AVEN Polyclonal Antibody
This is a AVEN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1’s ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.
Synonyms
1700013A01Rik,1700056A21Rik, Apoptosis caspase activation inhibitor, AVEN, AVEN, Cell death regulator Aven, mAven L, mAven S, MGC124011, OTTMUSP00000016129, PDCD12, Programmed cell death 12, RP23-52C15.2
Swiss Prot
Q9NQS1
Accession Number
NP_065104
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human AVEN
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
39 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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