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TAB3 Polyclonal Antibody

This is a TAB3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.

Synonyms

MAP3K7IP 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NAP1, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, Tab3, TAB3, TAK1 binding protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding p

Swiss Prot

Q8N5C8

Accession Number

BC032526

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human TAB3

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.2 mg/mL

Dilution

WB 1:200-1:1000, IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

79 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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