IPO4 Polyclonal Antibody
This is a IPO4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Importin-4is aproteinthat in humans is encoded by theIPO4gene. Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.
Synonyms
Imp4, Imp4b, Importin 4, Importin 4b, Importin-4, Importin-4b, Ipo4, IPO4, Ran binding protein 4, Ran-binding protein 4, RanBP4
Swiss Prot
Q8TEX9
Accession Number
BC003690
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human IPO4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.2 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
119 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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