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HYAL3 Polyclonal Antibody

This is a HYAL3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.

Synonyms

Hyal-3, HYAL3, HYAL3, Hyaluronidase 3, Hyaluronidase-3, Hyaluronoglucosaminidase 3, Hyaluronoglucosaminidase-3, LUCA-3, LUCA14, LUCA3, Lung carcinoma protein 3, Minna14

Swiss Prot

O43820

Accession Number

BC012892

Reactivity

Human, Rat

Immunogen

Recombinant protein of human HYAL3

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.2 mg/mL

Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

47 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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