(Z) -Leukadherin-1
(Z) -Leukadherin-1 (ADH-503 free base) is an orally active and allosteric CD11b agonist. (Z) -Leukadherin-1 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses[1].
Product Specifications
CAS Number
[2055362-72-4]
Product Name Alternative
ADH-503 (free base)
UNSPSC
12352005
Target
Complement System
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/z-leukadherin-1.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 4.55 mg/mL (ultrasonic; warming; heat to 60°C) |Methanol : < 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CC=C(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)C=C1
Molecular Formula
C22H15NO4S2
Molecular Weight
421.49
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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