MCM3AP Polyclonal Antibody
This is a MCM3AP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.
Synonyms
80 kDa MCM3 associated protein,80 kDa MCM3-associated protein, FLJ44336, FLJ45306, Germinal center associated nuclear protein, KIAA0572, MAP80, MCM3 import protein, MCM3 minichromosome maintenance deficient 3 associated protein, MCM3A, MCM3A, Mcm3ap, Minichromosome
Swiss Prot
O60318
Accession Number
BC104958
Reactivity
Human
Immunogen
Recombinant protein of human MCM3AP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
218 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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