GADD45B Polyclonal Antibody
This is a GADD45B Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
Synonyms
GA45B, GADD45 Beta, Gadd45b, GADD45BETA, Growth arrest and DNA damage inducible 45 beta, Growth arrest and DNA damage inducible beta, Growth arrest and DNA damage-inducible gene GADD45, beta, Growth arrest and DNA damage-inducible protein GADD45 beta, Growth arres
Swiss Prot
O75293
Accession Number
BC113466
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human GADD45B
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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