EDA2R Polyclonal Antibody

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.

9430060M22Rik, Ectodysplasin A2 isoform receptor, Ectodysplasin A2 receptor, EDA A2R, EDA-A2 receptor, EDA2R, EDAA2R, MGC124099, OTTMUSP00000019574, OTTMUSP00000019575, RP23-188N15.1, TNFRSF27, TNR27, Tumor necrosis factor receptor superfamily member 27, Tumor necrosis