EDA Polyclonal Antibody

The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.

ECTD1, Ectodermal dysplasia 1, anhidrotic, Ectodermal dysplasia protein, Ectodermal dysplasia, anhidrotic (hypohydrotic), Ectodysplasin A, Ectodysplasin A, membrane form, Ectodysplasin A, secreted form, ECTODYSPLASIN A1 ISOFORM, ECTODYSPLASIN A2 ISOFORM, ECTODYSPLASIN