RBBP8 Polyclonal Antibody

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.

COM1, COM1, CtBP interacting protein, CtBP-interacting protein, CtIP, DNA endonuclease RBBP8, JWDS, RB binding protein 8 endonuclease, RBBP-8, RBBP8, Retinoblastoma-binding protein 8, Retinoblastoma-interacting protein and myosin-like, Rim, SAE2, SCKL2, Sporulation in t