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ACLY Polyclonal Antibody

This is a ACLY Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms

ACL, Acly, ACLY, ATP citrate (pro-S) lyase, ATP citrate lyase, ATP citrate synthase, ATP-citrate (pro-S-) -lyase, ATP-citrate synthase, ATPcitrate synthase, ATPCL, Citrate cleavage enzyme, CLATP, OTTHUMP00000164773

Swiss Prot

P53396

Accession Number

BC006195

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ACLY

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

0.6 mg/mL

Dilution

WB 1:500-1:2000

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

121 kDa

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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