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IKZF3 Polyclonal Antibody

This is a IKZF3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

Product Specifications

Background

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

Synonyms

AIO, Aiolos, IKAROS family zinc finger 3 (Aiolos), IKAROS family zinc finger 3, Ikaros family zinc finger protein 3, IKZF 3, IKZF3, IKZF3, zinc finger DNA binding protein Aiolos, Zinc finger protein Aiolos, Zinc finger protein subfamily 1A 3 (Aiolos), Zinc finger pr

Swiss Prot

Q9UKT9

Accession Number

BC032707

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human IKZF3

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

IHC, ELISA

Purification Method

Affinity purification

Assay Type

Antibody

Concentration

1.6 mg/mL

Dilution

IHC 1:50-1:200

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Storage Conditions

Store at -20°C. Avoid freeze / thaw cycles.

Host or Source

Rabbit

Isotype

IgG

Available Sizes

Curated Selection

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