SETD2 Polyclonal Antibody
This is a SETD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Synonyms
EC 2.1.1.43, FLJ16420, FLJ22472, FLJ23184, FLJ45883, HBP231, HIF 1, HIF-1, HIF1, HIP-1, Histone lysine N methyltransferase SETD2, Histone-lysine N-methyltransferase SETD2, hSET2, HSPC069, Huntingtin interacting protein 1, Huntingtin interacting protein, Huntingtin intera
Swiss Prot
Q9BYW2
Accession Number
BC117162
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human SETD2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.2 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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