NAE1 Polyclonal Antibody

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

59 kDa, A 116A10.1, Amyloid beta precursor protein binding protein 1 59kD, Amyloid beta precursor protein binding protein 1 59kDa, Amyloid beta precursor protein binding protein 1, Amyloid beta precursor protein binding protein 1,59 kDa, Amyloid beta precursor