ALKBH2 Polyclonal Antibody
This is a ALKBH2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro) . Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
Synonyms
2OG Fe (II) oxy DC1,9530023G02, ABH 2, ABH2, alkB alkylation repair homolog 2, ALKB2, ALKBH2 alkB, ALKBH2, Alkylated DNA repair protein alkB homolog, Alkylated DNA repair protein alkB homolog 2, Alkylation repair homolog 2, Alpha ketoglutarate dependent dioxygenase
Swiss Prot
Q6NS38
Accession Number
BC070489
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human ALKBH2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
29 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
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