SOCS2 Polyclonal Antibody

This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway) . SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN) -gamma and by cytokine receptors such as growth horomone receptor.

CIS 2, CIS-2, CIS2, Cish 2, Cish2, Cytokine inducible SH2 protein 2, Cytokine-inducible SH2 protein 2, SOCS 2, SOCS-2, Socs2, SOCS2, SSI 2, SSI-2, SSI2, STAT induced STAT inhibitor 2, STAT-induced STAT inhibitor 2, STATI 2, STATI2, Suppressor of cytokine signaling 2