MCM6 Polyclonal Antibody
This is a MCM6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Synonyms
DNA replication licensing factor MCM6, MCG40308, Mcm6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6 minichromosome maintenance deficient 6, MCM6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (m
Swiss Prot
Q14566
Accession Number
BC032374
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human MCM6
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.8 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
93 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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