CFHR1 Polyclonal Antibody

This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

CFHL, CFHL1, CFHL1P, CFHR1, CFHR1P, Complement factor H related 1, Complement factor H related 1 pseudogene, Complement factor H related protein 1 precursor, Complement factor H-related protein 1, FHR 1, FHR-1, FHR1, FHR1, H factor (complement) like 1, H factor (comple