CERS4 Polyclonal Antibody
This is a CERS4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
Synonyms
Ceramide synthase 4, CerS4, FLJ12089, LAG1 homolog ceramide synthase 4, LAG1 longevity assurance homolog 4, LAG1, S. cerevisiae, homolog of,4, LASS 4, LASS4, LASS4 LAG1 homolog ceramide synthase 4, LASS4, TRAM homolog 1, Trh 1, Trh1
Swiss Prot
Q9HA82
Accession Number
NP_078828
Reactivity
Human
Immunogen
Synthetic peptide of human CERS4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.9 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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