IL5RA Polyclonal Antibody
This is a IL5RA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5) . The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Synonyms
CD125, CD125 antigen, CDw125, HSIL5R3, IL-5 receptor subunit alpha, IL-5R subunit alpha, IL-5R-alpha, IL-5RA, IL5R, IL5RA, IL5RA, Interleukin 5 Receptor alpha, Interleukin 5 Receptor alpha chain, Interleukin 5 receptor alpha subunit, Interleukin 5 receptor subunit alph
Swiss Prot
Q01344
Accession Number
NP_000555
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human IL5RA
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.8 mg/mL
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48 kDa
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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