CSTB Polyclonal Antibody
This is a CSTB Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1) .
Synonyms
CHROW21, CPI B, CPI-B, CST 6, CST6, CSTB, Cystatin B (stefin B), Cystatin B, Cystatin-B, CYTB, CYTB, EPM1, EPM1A, Liver thiol proteinase inhibitor, PME, Stefin-B, STF B, STFB, ULD
Swiss Prot
P04080
Accession Number
NP_000091
Reactivity
Human
Immunogen
Synthetic peptide of human CSTB
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.9 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
