NCR2 Polyclonal Antibody
This is a NCR2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Product Specifications
Background
Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336 (cluster of differentiation336) . NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.
Synonyms
Activating NK receptor NKp44, CD336, CD336 antigen, dJ149M18.1, LY95, Lymphocyte antigen 95 (activating NK receptor, NK p44), Lymphocyte antigen 95 homolog (activating NK receptor, NK p44), Lymphocyte antigen 95 homolog, Lymphocyte antigen 95, mouse, homolog of, Natur
Swiss Prot
O95944
Accession Number
NP_001186438
Reactivity
Human
Immunogen
Synthetic peptide of human NCR2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG
Available Sizes
Curated Selection
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